ISOLS Board Member
Francis Y. Lee, M.D., Ph.D., Honorary MBA
Professor with Tenure, Yale School of Medicine
Wayne O. Southwick Professor of Orthopaedics and Rehabilitation
Professor of Pathology, Professor of Biomedical Engineering,
Yale University School of Medicine, New Haven, U.S.A.
President, 2025-2026, Musculoskeletal Tumor Society (MSTS)
International Society of Limb Salvage (ISOLS), Board Member
Principal Investigator of National Institute of Health (NIH) Research Grants
It is my tremendous honor to interact with colleagues of the ISOLS as one of the Board Members. I am an orthopedic oncologist and clinical translational researcher in bone biology and cancer. I am currently a Professor with Tenure, Wayne O. Southwick Endowed Professor (2016-Present), at the Yale University, and formerly at the Columbia University (1999-2016), New York, USA.
My clinical research interest is in minimally invasive management and translational research in skeletal metastases and pathological fractures. I completed Orthopaedic Oncology Fellowship at MGH/Boston Children’s Hospital in 1997 (Drs. Francis Hornicek, Mark Gebhardt, and Henry Mankin) and completed Research Fellowship on bone repair under Dr. Thomas Einhorn, New York, in 1995. I have studied at many institutions in the world, and I appreciate international academic cultures. Thus, it is natural for me to become an active ISOLS member over 2 generations.
I also work for the members of the Musculoskeletal Tumor Society (MSTS) as MSTS President-Elect (2024-2025) and MSTS President (2025-2026). I am pondering upon “How can we do something different, new, and better for patients with skeletal metastases and pathological fractures?” To this end, I have been conducting clinical and translational research on bone-cancer interactions and inflammation as the Principal Investigator of National Institute of Health (NIH) Research Grants in the past 20 years. I received the AAOS Kappa Delta Award in 2016. I am Chair of the Grant Committee of the Orthopaedic Research and Education Foundation (OREF) and have served numerous NIH/DOD/OREF/AAOS Review Panels in USA.
I look forward to more collaborations and interactions with ISOLS members for better care of patients, advancement of science, and friendship.